People with chronic respiratory conditions (e.g., asthma or chronic obstructive pulmonary disease), cardiovascular diseases, anaemia, or compromised immune systems are more susceptible to the harmful effects of carbon monoxide.
Exposure to carbon monoxide can exacerbate these conditions and lead to severe health problems.

Impaired Respiratory Function
Many chronic health conditions, such as chronic obstructive pulmonary disease (COPD), asthma, or interstitial lung disease, are associated with impaired respiratory function. The reduced capacity of the respiratory system can hinder the body's ability to eliminate carbon monoxide, leading to increased susceptibility.
Cardiovascular Diseases
Individuals with cardiovascular diseases, such as heart failure or coronary artery disease, already have compromised oxygen delivery to tissues. Carbon monoxide further diminishes the oxygen-carrying capacity of the blood, intensifying the strain on the cardiovascular system.
Anaemia
Chronic health conditions, including certain types of anaemia, can result in a decreased ability of the blood to carry oxygen. Carbon monoxide competes with oxygen to bind to haemoglobin, exacerbating the impact of anaemia on oxygen transport.
Neurological Disorders
Individuals with neurological disorders, such as Parkinson's disease or multiple sclerosis, may have altered sensorimotor functions. Impaired coordination and weakened responses to environmental hazards, including carbon monoxide, can increase the risk of exposure.
Weakened Immune System
Chronic health conditions often involve a compromised immune system. Carbon monoxide poisoning can further stress the immune system, making individuals more susceptible to infections and secondary complications.
Reduced Ability to Detect Symptoms
Some chronic health conditions can affect sensory perception or cognitive function. Individuals may have a reduced ability to recognise the symptoms of carbon monoxide poisoning, delaying the identification of exposure.
Extended Recovery Periods
Individuals with chronic health conditions may experience longer recovery periods and increased vulnerability to complications following exposure to carbon monoxide. The gas can contribute to the exacerbation of existing health issues.